MTHFr genetic mutations-2 -This gene mutation is one example of an issue that can arise related to synthetic folate intake (folic acid) versus naturally occuring folate in foods. With this gene mutation, one can have a compromised ability to properly activate and use folate and also the synthetic folic acid can accumulate and cause health problems.

• MTHFr genetic mutations-2 -This gene mutation is one example of an issue that can arise related to synthetic folate intake (folic acid) versus naturally occuring folate in foods. With this gene mutation, one can have a compromised ability to properly activate and use folate and also the synthetic folic acid can accumulate and cause health problems.